Uses and Benefits of Bioidentical Progesterone  

By: Amber Hannah, Pharm.D. Candidate 2021 

 

Bioidentical hormones are man-made hormones that act quite similarly to the hormones made in the human body. This does not mean “natural”, but it is “structure” that is similar. They are used to treat men and women that have low hormone levels, menopausal symptoms, or out of balance hormones. Many people have been in search of finding a more natural approach to hormone replacement therapy, so bioidentical hormones can be that option for them. Hormones that are made are estrogen, progesterone, and testosterone. Some of these hormone forms are prescription, and others are custom-made by a pharmacist via doctor’s order, which is a compounded medication. 

 

Bioidentical Progesterone vs. Synthetic Progesterone 

Bioidentical progesterone is made to act like the hormones made in the body. Synthetic progesterone does not always act like the progesterone made in the body. Bioidentical is sometimes called “micronized natural progesterone”, which means breaking down progesterone into small particles to allow for steady absorption derived from a plant source. Bioidentical progesterone and synthetic progestins are structurally dissimilar and functionally different because it is chemically indistinguishable from progesterone in the body.   

 

Compounded Progesterone Dosage Forms 

Pills, Creams, Gels, Sprays, Vaginal inserts 

 

Benefits of Bioidentical Progesterone 

Progesterone has a great impact on function and quality of life. It supports pregnancy, helps regulate skin, mood, sleep, function of the thyroid, and libido. Because of the identical replication to progesterone, there are reduced side effects and risks, and there is enhanced effectiveness in treatment.  

 

Frequently Asked Questions (FAQs) 

  1. What are the signs of low progesterone? 
  1. Some signs of low progesterone include decreased libido, hot flashes, migraines/headaches, depression, anxiety, irregular menstrual cycle, breast soreness, vaginal dryness 
  1. How long can you stay on bioidentical hormones? 
  1. It varies patient to patient depending on treatment goals, conditions, and medical history. 
  1. Will bioidentical hormones help me lose weight? 
  1. With hormone imbalance, weight gain is prone to happen, but when given bioidentical progesterone, that can help promote weight management.  
  1. When should I take my progesterone? 
  1. Usually taken at bedtime and should be taken continuously as directed by doctor 

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References 

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